This surgery is usually done while you are under general anesthesia. That means you will be asleep and pain-free.
Healthy skin is taken from a place on your body called the donor site. Most people who are having a skin graft have a split-thickness skin graft. This takes the two top layers of skin from the donor site (the epidermis) and the layer under the epidermis (the dermis).
The donor site can be any area of the body. Most times, it is an area that is hidden by clothes, such as the buttock or inner thigh.
The graft is carefully spread on the bare area where it is being transplanted. It is held in place either by gentle pressure from a well-padded dressing that covers it, or by staples or a few small stitches. The donor-site area is covered with a sterile dressing for 3 to 5 days.
People with deeper tissue loss may need a full-thickness skin graft. This requires an entire thickness of skin from the donor site, not just the top two layers.
A full-thickness skin graft is a more complicated procedure. Common donor sites for full-thickness skin grafts include the chest wall, back, or abdominal wall.
Why the Procedure Is Performed
Skin grafts may be recommended for:
Areas where there has been infection that caused a large amount of skin loss
Loss of grafted skin (the graft not healing, or the graft healing slowly)
Reduced or lost skin sensation, or increased sensitivity
Uneven skin surface
Before the Procedure
Tell your surgeon or nurse:
What medicines you are taking, even drugs or herbs you bought without a prescription.
If you have been drinking a lot of alcohol.
During the days before surgery:
You may be asked to stop taking medicines that make it hard for your blood to clot. These include aspirin, ibuprofen, warfarin (Coumadin), and others.
Ask your surgeon which drugs you should still take on the day of your surgery.
If you smoke, try to stop. Smoking increases your chance of problems such as slow healing. Ask your doctor or nurse for help quitting.
On the day of the surgery:
Follow instructions about when to stop eating and drinking.
Take the drugs your surgeon told you to take with a small sip of water.
After the Procedure
You should recover quickly after split-thickness skin grafting. Full-thickness grafts need a longer recovery time. If you received this kind of graft, you may need to stay in the hospital for 1 to 2 weeks.
After you are discharged from the hospital, follow instructions on how to care for your skin graft, including:
Wearing a dressing for 1 to 2 weeks. Ask your provider how you should care for the dressing, such as protecting it from getting wet.
Protecting the graft from trauma for 3 to 4 weeks. This includes avoiding being hit or doing any exercise that might injure or stretch the graft.
Getting physical therapy, if your surgeon recommends it.
Most skin grafts are successful, but some do not heal well. You may need a second graft.
Debra G. Wechter, MD, FACS, general surgery practice specializing in breast cancer, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.