Intellectual disability is common. Half of children with this syndrome learn enough verbal skills to communicate. The cat-like cry becomes less noticeable over time.
Complications depend on the amount of intellectual disability and physical problems. Symptoms may affect the person's ability to care for themselves.
When to Contact a Medical Professional
This syndrome is most often diagnosed at birth. Your provider will discuss your baby's symptoms with you. It is important to continue regular visits with the child's providers after leaving the hospital.
Genetic counseling and testing is recommended for all people with a family history of this syndrome.
There is no known prevention. Couples with a family history of this syndrome who wish to become pregnant may consider genetic counseling.
Bacino CA, Lee B. Cytogenetics. In: Kliegman RM, Stanton BF, St Geme JW III, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016:chap 81.
Chad Haldeman-Englert, MD, FACMG, Fullerton Genetics Center, Asheville, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.