Streaked, whirled or mottled patchs of skin on the arms, legs, and middle of the body
Varying degrees of intellectual disability incluiding autism and learning disability
Exams and tests
A Wood's lamp examination of the skin lesions may help confirm the diagnosis. Your doctor may also recommend chromosome analysis or a further medical workup to discover any related medical problems.
There is no treatment for the hypopigmentation. Treatment consists of treating the symptoms. Cosmetics or clothing may be used to cover the hypopigmented spots if desired. Seizures, scoliosis, and other problems are treated as necessary.
What happens depends on the type and severity of symptoms that develop. In most cases, the skin pigment eventually returns to normal.
Discomfort and walking problems due to scoliosis
Emotional distress related to the physical appearance
Call your health care provider if your child exhibits an unusual pattern of the color of the skin.
James WD, Berger TG, Elston DM, Andrews' Diseases of the Skin: Clinical Dermatology. 11th ed. Philadelphia, Pa: Elsevier Saunders; 2011: chap 27.
Moss C. Mosaicism and linear lesions. In: Bolognia JL, Jorizzo JL, Schaffer JV, eds.: Dermatology. 3rd ed. Philadelphia, Pa: Elsevier Saunders; 2012:chap 61.
Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.