Lymphofollicular hyperplasia is an increase in the size of the lymph node follicles. These follicles contain normal white blood cells called lymphocytes. Your body produces more lymphocytes to help prevent bacteria, viruses, and other types of germs from entering the bloodstream.
Lymphadenopathy; Lymphofollicular hypertrophy
Armitage JO, Bierman PJ. Approach to the patient with lymphadenopathy and splenomegaly. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 23rd ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 168.
Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.