Scalded skin syndrome is caused by infection with certain strains of Staphylococcus bacteria. The bacteria produce a poison that causes the skin damage. The damage creates blisters, as if the skin were scalded. These blisters can occur at areas of the skin away from the initial site.
Scalded skin syndrome is found most commonly in infants and children under the age of 5.
Large areas of skin peel or fall away (exfoliation or desquamation)
Redness of the skin (erythema), which spreads to cover most of the body
Skin slips off with gentle pressure, leaving wet red areas (Nikolsky's sign)
Exams and Tests
The health care provider will perform a physical exam and look at the skin. The exam may show that the skin slips off when it is rubbed (positive Nikolsky's sign).
Call your health care provider or go to the emergency room if you have symptoms of this disorder.
The disorder may not be preventable. Treating any staphylococcus infection quickly can help.
Staphylococcal Scalded Skin Syndrome (Ritter Disease). In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 657.3.
Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.