Other tests may be needed. Family members may also need to be tested.
There is no specific treatment for this disorder. Platelet transfusions may be given to people who are having severe bleeding.
Glanzmann disease is a lifelong condition, and there is no cure. You should take special steps to try to avoid bleeding if you have this condition.
Anyone with a bleeding disorder should avoid taking aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen. These drugs can prolong bleeding times by preventing platelets from clumping.
Glanzmann disease is an inherited condition. There is no known prevention.
Macartney CA, Paredes N, Chan AKC. Disorders of coagulation in the neonate. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, Anastasi JI, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 152.
Nurden AT, Pillois X, Wilcox DA. Glanzmann thrombasthenia: state of the art and future directions. Semin Thromb Hemost. 2013;39;642-55. PMID: 23929305 www.ncbi.nlm.nih.gov/pubmed/23929305.
Yi-Bin Chen, MD, leukemia/bone marrow transplant program, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.