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Gastritis

Definition

Gastritis occurs when the lining of the stomach becomes inflamed or swollen.

Gastritis can last for only a short time (acute gastritis). It may also linger for months to years (chronic gastritis).

Causes

The most common causes of gastritis are:

  • Certain medicines, such as aspirin, ibuprofen, or naproxen
  • Heavy alcohol drinking
  • Infection of the stomach with a bacteria called Helicobacter pylori

Less common causes are:

  • Autoimmune disorders (such as pernicious anemia)
  • Backflow of bile into the stomach (bile reflux)
  • Cocaine abuse
  • Eating or drinking caustic or corrosive substances (such as poisons)
  • Extreme stress
  • Viral infection, such as cytomegalovirus and herpes simplex virus (more often occurs in people with a weak immune system)

Trauma or a severe, sudden illness such as major surgery, kidney failure, or being placed on a breathing machine may cause gastritis.

Symptoms

Many people with gastritis do not have any symptoms.

Symptoms you may notice are:

  • Loss of appetite
  • Nausea and vomiting
  • Pain in the upper part of the belly or abdomen

If gastritis is causing bleeding from the lining of the stomach, symptoms may include:

Exams and Tests

Tests that may be needed are:

  • Complete blood count (CBC) to check for anemia or low blood count
  • Examination of the stomach with an endoscope (esophagogastroduodenoscopy or EGD)
  • H. pylori tests
  • Stool test to check for small amounts of blood in the stools, which may be a sign of bleeding in the stomach

Treatment

Treatment depends on what is causing the problem. Some of the causes will disappear over time.

You may need to stop taking aspirin, ibuprofen, naproxen, or other medicines that may be causing gastritis. Always talk to your doctor before stopping any medicine.

You may use other over-the-counter and prescription drugs that decrease the amount of acid in the stomach, such as:

  • Antacids
  • H2 antagonists: famotidine (Pepsid), cimetidine (Tagamet), ranitidine (Zantac), and nizatidine (Axid)
  • Proton pump inhibitors (PPIs) -- omeprazole (Prilosec), esomeprazole (Nexium), iansoprazole (Prevacid), rabeprazole (AcipHex), and pantoprazole (Protonix)

Antacids may be used to treat chronic gastritis caused by infection with Helicobacter pylori bacteria.

Outlook (Prognosis)

The outlook depends on the cause, but is often very good.

Possible Complications

Blood loss and increased risk of gastric cancer can occur.

When to Contact a Medical Professional

Call your health care provider if you develop:

  • Pain in the upper part of the belly or abdomen that does not go away
  • Black or tarry stools
  • Vomiting blood or coffee-ground-like material

Prevention

Avoid long-term use of substances that can irritate your stomach such as aspirin, anti-inflammatory drugs, or alcohol.

References

Kuipers E, Blaser MJ. Acid peptic disease. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 141.

Lee EL, Feldman M. Gastritis and gastropathies. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 51.


Review Date: 1/22/2013
Reviewed By: George F Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program San Diego, California. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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