Bullous pemphigoid is a skin disorder characterized by large blisters.
Bullous pemphigoid is an autoimmune disorder which occurs when the body's immune system attacks and destroys healthy body tissue by mistake.
This disorder usually occurs in older persons and is rare in young people. Symptoms come and go. In most patients, the condition goes away within 5 years.
Some people have no symptoms. Others may have mild redness, itching and irritation.
In many cases, they are many blisters, called bullae. Blisters are usually located on the arms, legs, or middle of the body. The blisters may break open and form ulcers or open sores. Some people also develop blisters in the mouth.
Scott M, Werth VP. Bullous pemphigoid. In: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson I, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. 4th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 32.
Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.