Acquired platelet function defects are conditions that prevent clotting elements in the blood called platelets from working as they should. The term acquired means these conditions are not present at birth.
Acquired qualitative platelet disorders; Acquired disorders of platelet function
Platelet disorders can affect the number of platelets, how well they function, or both. A platelet disorder affects normal blood clotting.
Disorders that can cause problems in platelet function include:
Your symptoms do not improve after you are treated for an acquired platelet function defect
Using medicines as directed can reduce the risk of drug-related acquired platelet function defects. Treating other disorders may also reduce the risk. Some cases cannot be prevented.
Diz-Kucukkaya R, Lopez JA, Acquired disorders of platelet function. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, Anastasi JI, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 132.
Jobe S, Di Paola J. Congenital and acquired disorders of platelet function. In: Kitchens CS, Kessler CM, Konkle BA, eds. Consultative Hemostasis and Thrombosis. 3rd ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 10.
Rita Nanda, MD, Assistant Professor of Medicine, Section of Hematology/Oncology, University of Chicago Medicine, Chicago, IL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.