Treatment depends on the cause of the problem. Avoiding medicines that lead to this condition may quickly relieve symptoms.
Limiting salt and fluid in the diet can improve swelling and high blood pressure. Limiting protein in the diet can help control the buildup of waste products in the blood (azotemia) that can lead to symptoms of acute kidney failure.
If dialysis is necessary, it usually is required for only a short time.
Corticosteroids or stronger anti-inflammatory medicines such as cyclophosphamide can sometimes be helpful.
Most often, interstitial nephritis is a short-term disorder. In rare cases, it can cause permanent damage, including chronic kidney failure.
Acute interstitial nephritis may be more severe and more likely to lead to long-term or permanent kidney damage in older people.
Charles Silberberg, DO, private practice specializing in nephrology, affiliated with New York Medical College, Division of Nephrology, Valhalla, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.